Oncologists and other cancer doctors choose what course of treatment to pursue to their patient. There are numerous options. There exists no universal treatment course for pleural mesothelioma cancer patients. This is because of the relative rareness of the disease, the high mortality rate and low treatment success rate, and the few scientific studies to provide meaningful statistics.

While prospects for patients with mesothelioma have been bleak, doctors have been making progress. Treatments for cancer are traditionally surgery (taking out the tumor and surrounding tissue), radiation (killing the cancerous cells with radiation), and chemotherapy (poisoning the cancerous cells.) There are problems with all three. Traditional radiation therapy has not worked well with mesothelioma patients. Researches, concerned about damage to healthy tissue, are looking for ways to aim radiation directly at tumors.

The mesothelial tissue around the tumor is removed by surgery. This surgery is extensive and it is not clear how much the patient benefits. Most chemotherapy medication that work on other cancers typically do not work on mesothelioma, and different mixtures of these drugs have not been successful. Like radiation, researchers are focusing their work on controlling the physical location of the treatment with an emphasis on the pleural cavity.

Many advanced techniques in cancer treatment are tried on mesothelioma patients because of its high fatality rate. Such treatments include anti-angiogenesis drugs like thalidomide and biologic therapies agent interleukin 2. The new drug pemetrexed (brand name Alimta) has shown good results in extending life with mesotheliomas..

Oncologists consider the stage of mesothelioma, the location of the tumor, the patient’s age and state of health at the time. Two therapies that are extremely cutting-edge in fighting cancer are called photodynamic and gene therapy. Patients afflicted with mesothelioma are benefitting in these clinical trials.